In 1994, the World Missions Department at Advent Christian General Conference received a report that refugees escaping the horrors of the civil war in Liberia had emigrated to Ghana and formed a growing Advent Christian work there.

By February of 1995, Ghana was endorsed as an Advent Christian mission field by the ACGC Executive Council.

Liberian pastor Rev. Amos Gbaa initially led the work in Ghana, where some churches were formed in refugee camps and others were started in the surrounding countryside.

The work grew under Rev. Gbaa. When he later immigrated to the United States to attend school, Rev. Gbaa planted an Advent Christian church among Liberian and other international immigrants in Providence, Rhode Island.

Another Liberian, Pastor Andrew Wreh, succeeded Rev. Gbaa as head of the Ghana Advent Christian Conference. As the Ghana churches grew among Liberian refugees as well as native Ghanaians, their Conference leadership began to shift from Liberian to Ghanaian. Other leaders have been Pastor Samuel Moore, Pastor Newman Djikomale and Pastor Simon Bissah.

In 2001, a provisional constitution was recommended for the Ghana conference.

2004 brought a determination to undergo a serious soul-winning drive in surrounding villages which were predominantly pagan areas. Places for worship were sought.

In 2005 the conference hoped to expand its work into the Republic of Togo, its neighbor to the east. A pastor sent to the Republic of Togo returned a positive report. Work began on erecting a structure for worship at Nsawam, Ghana, now the headquarters church of the conference. Structures also began for the Accra branch, which worshipped in a school building but was most promising in terms of rapid increase in membership, and for the Nsakyi branch.

2007 and 2008 were busy years, opening five new churches and fellowships with 450 members. The government of Ghana starting deporting Liberian refugees back to Liberia, affecting our two Liberian refugee churches in Buduburam. Rev. Abraham David of Liberia was called to assist.

In May 2009, Area Director Russell Carle and Nigerian Conference President Christian Paul visited Emmanuel AC Church at the Liberian refugee settlement in Buduburam, and churches in three  other regions. They were warmly received and enjoyed worship, fellowship, and travel, ordained six new pastors into the conference, and joined youth on a field trip to beautiful Kakum National Park.